Dental practitioners should be aware of the possible causes of intraoral swellings in both children and adults. Information and translations of sialometaplasia, necrotizing in the most comprehensive dictionary definitions resource on the web. Necrotizing sialometaplasia ns is an uncommon benign reactive necrotizing inflammatory process involving minor salivary gland that often mimics malignancy both clinically and histopathologically. Necrotizing sialometaplasia ns is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach.
A further five cases were reported the following year by dunlap and barker. This pathological lesion was first reported in 1973 by abrams et al. It is considered by some authors to be a distinct entity 1,2 and by others to be part of the spectrum of necrotizing sialometaplasia ns. The appearance of some conditions in children may differ from their characteristic appearance in adults. Oral examination revealed a nodule consisting of two lobules on the right side that measured 2. Mouth cancer acute necrotising sialometaplasia sir, i read with interest the letter from gogna et al. Necrotising sialometaplasia is extremely rare there are barely 200 cases reported in the world literature. All subsequent reports of necrotizing sialometaplasia stress the. Necrotizing sialometaplasia uncommon locally destructive inflammatory condition of the salivary glands. The lesions are characterized histologically by an extensive necrosis of the salivary gland tissue together with squamous metaplasia of. Necrotizing sialometaplasia a diagnostic conundrum. A case of sialometaplasia of the soft palate is reported in a 2yearold girl 3 months after she had an adenoidectomy. Necrotizing sialometaplasia ns is a nonneoplastic inflammatory condition of the salivary glands. In the who classification of salivary gland tumors, ns is classified under the group of tumor.
Necrotizing sialometaplasia of hard palate a case report. It appears as an aggressive looking lesion in an adult possibly resembling squamous cell carcinoma and mucoepidermoid carcinoma. Here we report a case of necrotizing sialometaplasia in a female on left side of hard palate mimicking carcinoma. Dec 05, 2016 enterocolitis necrotizante 2016 slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Enterocolitis necrotizante 2016 linkedin slideshare. A rare site of socalled necrotizing sialometaplasia. It may clinically and microscopically resemble squamous cell or mucoepidermoid carcinoma but is histologically.
The vast majority 80% of cases affect the minor salivary glands of the palate, while other sites include gum behind the lower wisdom teeth retromolar pad, lip, tongue and cheek. Necrotizing sialometaplasia ns is a benign disease showing inflammatory response which occurs in minor salivary glands mimicking a malignant lesion both clinically and histologically. Necrotizing sialometaplasia of the hard palate in a patient. Dec 17, 2015 necrotizing sialometaplasia nsm is a rare benign, inflammatory disease of both major and minor salivary glands, although more commonly reported in the minor glands of the palate. The relationship of its pathogenesis to its clinical characteristics. Necrotizing sialometaplasia of the palate j canadian dental association 2007. Although entirely benign and requiring no treatment, due. Fascitis necrotizante tratamiento pdf cura fascitis plantar. Necrotizing sialometaplasia of the palate associated with angiocentric tcell lymphoma. Necrotizing sialometaplasia international journal of. To the best of our knowledge, only 22 cases of sans have been reported, mostly on salivary palatal glands. We report the case of a healthy 26yearold man with a painless swelling in the hard palate near the middle raphe, asymptomatic, well limited, and raised edges.
Pdf necrotizing sialometaplasia ns is a selflimiting inflammatory disease, that involves salivary glands, more frequently the minor ones. Mar 29, 2018 necrotizing sialometaplasia ns is a nonneoplastic inflammatory condition of the salivary glands. Necrotizing sialometaplasia definition of necrotizing. Jul 11, 2016 necrotizing sialometaplasia is a rare, benign, selflimiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate. Necrotizing sialometaplasia ns which mimics malignancy both clinically and histopathologically is an uncommon benign, selflimiting inflammatory disease of the mucussecreting minor salivary glands. It predominantly affects salivary tissue and usually involves the palate, although it has. Necrotizing sialometaplasia of the hard palate in a. Necrotizing sialometaplasia is a completely benign lesion that is most likely caused by ischemia secondary to trauma examples of causes could be dental injection or hot liquid burn. In august 2015 a 43yearold caucasian female with an unremarkable medical his. Necrotizing sialometaplasia is a rare inflammatory necrotizing reactive process that can involve minor and major salivary glands. The characteristic clinical presentation can perplex the clinician and may be mistaken for a malignant neoplasm, such as mucoepidermoid carcinoma, as well as. Mucus gland infarct with squamous epithelial metaplasia in the lung. In 1973, abrams et al first reported this condition.
Necrotizing sialometaplasia nsm is an uncommon inflammatory condition that affects salivary glands. Surgical management of necrotizing sialometaplasia of. The vast majority of cases occur on the posterior lateral hard palate. A 38yearold man with bilateral ulcerative painful lesions at the junction of the hard and soft. A case of necrotizing sialometaplasia ns is presented in a female patient, who initially presented as a suspected head and neck malignancy. Lisa franklin is an oral pathologist who presented a forensics lecture to the residency. Necrotizing sialometaplasia wikipedia republished wiki 2. Necrotizing sialometaplasia ns is a benign, ulcerative lesion, usually located towards the back of the hard palate. Necrotizing sialometaplasia of major salivary glands.
Necrotizing sialometaplasia in the setting of acute and chronic sinusitis. The clinical and histopathologic features of necrotizing sialometaplasia often simulate those of malignancies such as squamous cell carcinoma or salivary gland malignancy. Necrotizing sialometaplasia an important diagnosis. Subacute necrotizing sialadenitis sans is a selflimiting inflammatory lesion of the minor salivary glands of unknown cause. Necrotizing sialometaplasia ns is a benign disease showing inflammatory response which occurs in minor salivary glands mimicking a malignant lesion both clinically as well as histopathologically.
Dominguezmalagon h, mosquedataylor a, canovaldez am. Necrotizing sialometaplasia a diagnostic conundrum dental. An association with neoplasia, such as parotid tumors, false vocal cord squamous cell carcinoma, and maxillary sinus carcinoma, is also reported. Sialometaplasia definition of sialometaplasia by medical. The lesions are characterized histologically by an extensive necrosis of the salivary gland tissue together with squamous metaplasia of the ducts. Jun 23, 2014 necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma, both clinically and histologically, that creates diagnostic dilemma leading to unwarranted aggressive surgery. Till date, the diagnosis of ns remains a challenge. Case report ct findings of necrotizing sialometaplasia.
Necrotizing sialometaplasia nsm is a rare benign, inflammatory disease of both major and minor salivary glands, although more commonly reported in the minor glands of the palate. Gland tissue ischaemia has been proposed as the aetiology. The lesion is believed to be the result of vascular ischemia that may be initiated by trauma. Ct findings of necrotizing sialometaplasia a suomalainen et al 531 dentomaxillofacial radiology. Necrotizing sialometaplasia is a disease process which affects minor salivary glands. Enterocolitis necrotizante 2016 slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Franklin has a great style of presentation, and i felt it was important to show others that oral. The lesions heal on their own with or without biopsy.
Physicians should be aware of its clinical and histological traits in order to avoid unnecessary disfiguring surgery. The reason for biopsy is to rule out cancer from their worrisome clinical presentation. If you continue browsing the site, you agree to the use of cookies on this website. The ensuing inflammation causes squamous metaplasia of ducts and hyperplasia of the surface stratified squamous epithelium. Often painless, the condition is selflimiting and should heal in 610 weeks. The cause is local ischemia producing infarction of salivary acini. Experimental study of necrotizing sialometaplasia of the palate in rats. This selflimiting benign lesion is easily confused with malignant tumors. Surgical management of necrotizing sialometaplasia of palate. Necrotizing sialometaplasia was first described in 1973 by abrams, melrose and howell1. The aim is to add to the existing literature on this condition. Necrotizing sialometaplasia necrotizing sialometaplasia is. Some predisposing factors such as smoking, use of alcohol, denture wearing, recent surgery, traumatic injuries. Necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma, both clinically and histologically, that creates diagnostic dilemma leading to unwarranted aggressive surgery.
Necrotizing sialometaplasia is a rare, benign inflammatory disease of the minor mucous salivary glands usually caused by glandular ischemia or trauma, that can mimic malignancy, but has a selflimiting character. Necrotizing sialometaplasia necrotizing sialometaplasias. Mar 26, 2011 necrotizing sialometaplasia ns is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach. Most cases of necrotizing sialometaplasia appear to arise spontaneously, whereas others are associated with a history of trauma, vomiting, 18, 19 radiation therapy, or surgery.
Necrotizing sialometaplasia is an uncommon inflammatory condition that affects salivary glands. It is thought to be the result of an ischemic event of the vasculature supplying the salivary gland lobules. The lesion begins acutely with swelling and pain or. Definition of sialometaplasia, necrotizing in the dictionary.
Apr 16, 2017 these oral pathology videos are mostly recorded in urdu, which was especially recorded to help me out in my second year so i didnt have to go through the book again and again. Necrotizing sialometaplasia is a reactive lesion of salivary gland origin. Necrotizing sialometaplasia is a rare, benign, selflimiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate. It is thought to be caused by ischemic necrosis death of tissue due to lack of blood supply of minor salivary glands in response to trauma. Necrotizing sialometaplasians which mimics malignancy both clinically and histopathologically is an uncommon benign, selflimiting inflammatory disease of the mucussecreting minor salivary glands.